Some temple help, how to get rid of a path?

I would try pathing over it and using a sacrificial chamber to remove it and replace it with something else

Only way would be to build around it, remove it with a sac chamber upgrade and delete the extra later, when you have a smithy and sac chamber. Not sure if sac chamber accepts roads though.

You can make a big loop and sacrifice the path. Just make sure you have a sac and the piece to make a loop ready in the same turn (don’t make the loop without the sacrifice ready). 

If you connect the snake to the right entrance so it loops and use a sacrificial chamber to sacrifice the dead room, make sure to have a sacrifice when you loop (if that's what you're asking)